Compound Q&A

How is RG7227 (CAS: 850876-88-9) typically synthesized?

Answer

RG7227, ITMN-191, RO5190591
RG7227 (CAS: 850876-88-9) can be synthesized via a multi-step process involving protected amino acid derivatives and subsequent deprotection steps. Commonly, the reaction is performed in the presence of a strong base and a suitable catalyst, yielding a high purity product with good selectivity and a high yield of up to 90%.

About

English Name RG7227, ITMN-191, RO5190591
Molecular Formula C35H46FN5O9S
Molecular Weight 731.83 g/mol
SMILES O=C(OC(C)(C)C)N[C@H]1CCCCC/C=C\[C@@H]2[C@](NC(=O)[C@H]3N(C1=O)C[C@@H](C3)OC(=O)N1Cc3c(C1)cccc3F)(C2)C(=O)NS(=O)(=O)C1CC1
InChIKey ZVTDLPBHTSMEJZ-DUDMPJCFSA-N
Last Updated: 2025-10-13 15:08

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