Compound Q&A

How is Methyl 5-isoindolinecarboxylate hydrochloride (CAS: 127168-93-8) typically synthesized?

Answer

Methyl 5-isoindolinecarboxylate hydrochloride (1:1)
Methyl 5-isoindolinecarboxylate hydrochloride (CAS: 127168-93-8) is typically synthesized through the reaction of 5-isoindolinecarboxylic acid with methyl alcohol in the presence of hydrochloric acid. The reaction involves esterification and salt formation, yielding the target compound with good selectivity and yield.

About

English Name Methyl 5-isoindolinecarboxylate hydrochloride (1:1)
Molecular Formula C10H12ClNO2
Molecular Weight 213.66 g/mol
SMILES Cl.COC(=O)c1ccc2CNCc2c1
InChIKey UCJNRYHJEDJKAI-UHFFFAOYSA-N
Last Updated: 2025-10-13 15:08

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