Compound Q&A
How is 3-Chloro-2-pyrazinecarboxylic acid (CAS: 27398-39-6) typically synthesized?
Answer
3-Chloro-2-pyrazinecarboxylic acid is commonly synthesized via the chlorination of 2-pyrazinecarboxylic acid. This process involves the reaction of 2-pyrazinecarboxylic acid with thionyl chloride in the presence of a base such as pyridine. The yield is typically around 70-80%, with good selectivity toward the monochlorinated product.
About
CAS No
27398-39-6
English Name
3-Chloro-2-pyrazinecarboxylic acid
Molecular Formula
C5H3ClN2O2
Molecular Weight
158.54 g/mol
SMILES
C1=CN=C(C(=N1)C(=O)O)Cl
InChIKey
PMRPVXLESNMKLG-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55
