Compound Q&A

How is 2-Isobutoxy-1,2-diphenylethanone (CAS: 22499-12-3) typically synthesized?

Answer

2-Isobutoxy-1,2-diphenylethanone
2-Isobutoxy-1,2-diphenylethanone (CAS: 22499-12-3) is typically synthesized via the reaction of isobutyronitrile with phenylacetyl chloride in the presence of a base such as triethylamine. The reaction yields a high selectivity and good yield, making it a versatile intermediate in organic synthesis.

About

CAS No 22499-12-3
English Name 2-Isobutoxy-1,2-diphenylethanone
Molecular Formula C18H20O2
Molecular Weight 268.36 g/mol
SMILES CC(C)COC(C1=CC=CC=C1)C(=O)C2=CC=CC=C2
InChIKey JMVZGKVGQDHWOI-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55

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