Compound Q&A
How is (11R,26R)-4,5,19,20-Tetramethoxy-10,25-dimethyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.2~13,16~.1~3,7~.1~18,22~.0~11,36~.0~26,33~]hexatriaconta-1(30),3(36),4,6,13,15,18(33),19,21,28,31,34-dodecaene (CAS: 518-94-5) typically synthesized?
Answer
![(11R,26R)-4,5,19,20-Tetramethoxy-10,25-dimethyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.2~13,16~.1~3,7~.1~18,22~.0~11,36~.0~26,33~]hexatriaconta-1(30),3(36),4,6,13,15,18(33),19,21,28,31,34-dodecaene](https://static.chemtradehub.com/structs/518/518-94-5-dc84.webp "(11R,26R)-4,5,19,20-Tetramethoxy-10,25-dimethyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.2~13,16~.1~3,7~.1~18,22~.0~11,36~.0~26,33~]hexatriaconta-1(30),3(36),4,6,13,15,18(33),19,21,28,31,34-dodecaene")
Synthesis of this compound involves multi-step reactions including ring closure, methylation, and methoxylation. Commonly, a starting material undergoes ring formation via a Diels-Alder reaction, followed by selective methylation and methoxylation steps. The use of Lewis acids and organometallic reagents is typical in this process, yielding the target compound with high selectivity and good yield.
About
CAS No
518-94-5
English Name
(11R,26R)-4,5,19,20-Tetramethoxy-10,25-dimethyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.2~13,16~.1~3,7~.1~18,22~.0~11,36~.0~26,33~]hexatriaconta-1(30),3(36),4,6,13,15,18(33),19,21,28,31,34-dodecaene
Molecular Formula
C38H42N2O6
Molecular Weight
622.76 g/mol
SMILES
CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC=C(O3)C=C7)N(CCC6=CC(=C5OC)OC)C)OC)OC
InChIKey
ANOXEUSGZWSCQL-LOYHVIPDSA-N
Last Updated: 2025-10-13 12:55
![(11R,26R)-4,5,19,20-Tetramethoxy-10,25-dimethyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.2~13,16~.1~3,7~.1~18,22~.0~11,36~.0~26,33~]hexatriaconta-1(30),3(36),4,6,13,15,18(33),19,21,28,31,34-dodecaene — Hubei Yunmei Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ceb7d92b2de6e8e95a4ae0/67ceb7d92b2de6e8e95a4ae0-logo.webp){kind=logo}
![(11R,26R)-4,5,19,20-Tetramethoxy-10,25-dimethyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.2~13,16~.1~3,7~.1~18,22~.0~11,36~.0~26,33~]hexatriaconta-1(30),3(36),4,6,13,15,18(33),19,21,28,31,34-dodecaene — Shanghai Analytical Rocky Experimental Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdcfdf57537e5c8069ad2d/67cdcfdf57537e5c8069ad2d-logo.webp){kind=logo}