Compound Q&A
How is 3-Chloro-2,5,6-trifluoropyridine (CAS: 2879-42-7) typically synthesized?
Answer
3-Chloro-2,5,6-trifluoropyridine is synthesized through the electrophilic fluorination of 3-chloropyridine followed by the alkylation of the resulting 2,5,6-trifluoropyridine with a chlorinating agent. Commonly, the reaction is catalyzed by Lewis acids such as aluminum chloride, and the process involves high yields and good selectivity.
About
CAS No
2879-42-7
English Name
3-Chloro-2,5,6-trifluoropyridine
Molecular Formula
C5HClF3N
Molecular Weight
167.52 g/mol
SMILES
C1=C(C(=NC(=C1Cl)F)F)F
InChIKey
OROKHXKJSDPRET-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18
