Compound Q&A

How is 1,1,1-Trichloro-2,2,2-trifluoroethane (CAS: 354-58-5) typically synthesized?

Answer

1,1,1-Trichloro-2,2,2-trifluoroethane
1,1,1-Trichloro-2,2,2-trifluoroethane (CAS: 354-58-5) is typically synthesized via the chlorination of 2,2,2-trifluoroethanol in the presence of hydrochloric acid as the catalyst. The process involves the addition of chlorine to the fluorinated alcohol under controlled conditions to ensure high selectivity and yield. The reaction is exothermic and requires careful temperature control to prevent the runaway reaction.

About

CAS No 354-58-5
English Name 1,1,1-Trichloro-2,2,2-trifluoroethane
Molecular Formula C2Cl3F3
Molecular Weight 187.38 g/mol
SMILES C(C(Cl)(Cl)Cl)(F)(F)F
InChIKey BOSAWIQFTJIYIS-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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