Compound Q&A
How is 1-(5-Pyrimidinyl)ethanone (CAS: 10325-70-9) typically synthesized?
Answer
1-(5-Pyrimidinyl)ethanone (CAS: 10325-70-9) is typically synthesized via a condensation reaction between ethyl acetoacetate and 5-chloropyrimidine. The reaction is performed in a polar aprotic solvent such as acetonitrile, and a strong base such as potassium hydroxide is used as a catalyst. The product is obtained with a yield of around 70-80%.
About
CAS No
10325-70-9
English Name
1-(5-Pyrimidinyl)ethanone
Molecular Formula
C6H6N2O
Molecular Weight
122.13 g/mol
SMILES
CC(=O)C1=CN=CN=C1
InChIKey
COTYNDRSENVEFI-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18
