Compound Q&A

How is Vardenafil Hydrochloride Trihydrate (CAS: 330808-88-3) typically synthesized?

Answer

Vardenafil Hydrochloride Trihydrate
Vardenafil Hydrochloride Trihydrate is typically synthesized via a multi-step process involving the synthesis of the parent vardenafil molecule followed by the addition of hydrochloric acid and water to form the trihydrate. The synthesis involves protecting groups, coupling reactions, and deprotection steps. The final product is crystallized from a suitable solvent, and the trihydrate form is obtained by hydrating the hydrochloride salt under controlled conditions.

About

English Name Vardenafil Hydrochloride Trihydrate
Molecular Formula C23H39ClN6O7S
Molecular Weight 579.12 g/mol
SMILES CCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C.O.O.O.Cl
InChIKey FBCDRHDULQYRTB-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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