Compound Q&A

How is 3,4-Dimethoxy-3-cyclobutene-1,2-dione (CAS: 5222-73-1) typically synthesized?

Answer

3,4-Dimethoxy-3-cyclobutene-1,2-dione
3,4-Dimethoxy-3-cyclobutene-1,2-dione (CAS: 5222-73-1) can be synthesized via a multistep process involving the reaction of methanol with acetaldehyde followed by the formation of the dione. Commonly used catalysts include sulfuric acid, and the reaction yields are typically around 75-85%. Selectivity and yield can be improved with optimized conditions and catalysts.

About

CAS No 5222-73-1
English Name 3,4-Dimethoxy-3-cyclobutene-1,2-dione
Molecular Formula C6H6O4
Molecular Weight 142.11 g/mol
SMILES COC1=C(C(=O)C1=O)OC
InChIKey SZBNZTGCAMLMJY-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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