Compound Q&A
How is Dimethyl acetamidomalonate (CAS: 60187-67-9) typically synthesized?
Answer
Dimethyl acetamidomalonate (CAS: 60187-67-9) is typically synthesized through the amidation of malonoyl chloride with dimethylamine. The reaction involves the condensation of malonoyl chloride with dimethylamine in the presence of an appropriate base, such as pyridine. The yield and selectivity of the reaction can be enhanced by using anhydrous conditions and appropriate catalysts.
About
CAS No
60187-67-9
English Name
Dimethyl acetamidomalonate
Molecular Formula
C7H11NO5
Molecular Weight
189.17 g/mol
SMILES
CC(=O)NC(C(=O)OC)C(=O)OC
InChIKey
CHQXZPUFDGYORW-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18
