Compound Q&A
What is Thapsigargin (CAS: 67526-95-8)?
Answer
Thapsigargin is a naturally occurring diterpene that acts as a potent and selective inhibitor of the endoplasmic reticulum calcium ATPase (ER-CAATPase), affecting cellular calcium homeostasis. It is used in research for studying intracellular calcium signaling and has potential therapeutic applications in cancer treatment.
About
CAS No
67526-95-8
English Name
Thapsigargin
Molecular Formula
C34H50O12
Molecular Weight
650.76 g/mol
SMILES
CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)C(=CC)C)C(=C2[C@H]1[C@@](C)(OC(=O)C)C[C@@H]([C@]1([C@H]2OC(=O)[C@@]1(C)O)O)OC(=O)CCC)C
InChIKey
IXFPJGBNCFXKPI-LGJGSQFISA-N
Last Updated: 2025-10-12 15:22
