Compound Q&A

How is 2-ethynylaniline (CAS: 52670-38-9) typically synthesized?

Answer

2-ethynylaniline
2-Ethynylaniline can be synthesized via the reaction of aniline with acetylene in the presence of a copper catalyst. The reaction involves electrophilic aromatic substitution and can be carried out under mild conditions. The yield is generally good, and the selectivity is high due to the presence of a strong electron-withdrawing group.

About

CAS No 52670-38-9
English Name 2-ethynylaniline
Molecular Formula C8H7N
Molecular Weight 107.15599999999999 g/mol
SMILES C#CC1=CC=CC=C1N
InChIKey RNVCVTLRINQCPJ-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10

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