Compound Q&A
How is 2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one (CAS: 85326-06-3) typically synthesized?
Answer
![2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one](https://static.chemtradehub.com/structs/853/85326-06-3-5d99.webp "2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one")
2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one can be synthesized through a multi-step process involving the condensation of 2-amino-6-oxopurine and (2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-carbaldehyde. The reaction is carried out in the presence of a catalyst such as palladium acetate. The process yields a high purity product with good selectivity and a yield of approximately 75-80%.
About
CAS No
85326-06-3
English Name
2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one
Molecular Formula
C10H13N5O3
Molecular Weight
251.25 g/mol
SMILES
O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](CO)CC3
InChIKey
OCLZPNCLRLDXJC-NTSWFWBYSA-N
Last Updated: 2025-10-10 21:10
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