Compound Q&A

How is 1-Bromo-2-chloro-3-fluorobenzene (CAS: 883499-24-9) typically synthesized?

Answer

1-Bromo-2-chloro-3-fluorobenzene
1-Bromo-2-chloro-3-fluorobenzene is typically synthesized via the Friedel-Crafts alkylating agent reaction or through halogenation of 1,2-dichloro-3-fluorobenzene using bromine. The reaction is catalyzed by aluminum bromide, and the product is isolated by recrystallization. This method ensures high selectivity and yield, making it a reliable synthesis route.

About

English Name 1-Bromo-2-chloro-3-fluorobenzene
Molecular Formula C6H3BrClF
Molecular Weight 209.45 g/mol
SMILES C1=CC(=C(C(=C1)Br)Cl)F
InChIKey GTIWFNAUYPVPAT-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10

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