How is (2R)-4-Ammonio-2-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoate (CAS: 80445-78-9) typically synthesized?

This compound is typically synthesized through a multi-step process involving the reaction of a primary amine with a carboxylic acid chloride. The synthesis involves the use of a mild carbodiimide as a coupling agent and a catalytic amount of a base. The process yields a high purity product with good selectivity and a yield of about 75-85%.