Compound Q&A

How is 4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}phenylalanine (CAS: 80102-27-8) typically synthesized?

Answer

4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}phenylalanine
4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}phenylalanine (CAS: 80102-27-8) is synthesized through a multi-step process involving peptide coupling, protection of hydroxyl groups, and subsequent deprotection. Commonly, a protected amino acid is coupled with a protected carboxylic acid derivative under mild conditions, followed by deprotection and purification steps. This compound is often synthesized using standard reagents such as HBTU, DIPEA, and TFA.

About

CAS No 80102-27-8
English Name 4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}phenylalanine
Molecular Formula C15H21NO4
Molecular Weight 279.33599999999996 g/mol
SMILES CC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OC(C)(C)C
InChIKey JYRWNPUFECDJCX-GFCCVEGCSA-N
Last Updated: 2025-10-10 19:08

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