Compound Q&A

How is 2,4-Difluoro-1-isocyanatobenzene (CAS: 59025-55-7) typically synthesized?

Answer

2,4-Difluoro-1-isocyanatobenzene
2,4-Difluoro-1-isocyanatobenzene is typically synthesized by treating 2,4-difluorophenol with phosgene in the presence of a base such as pyridine. The reaction proceeds through the formation of a chlorophenyl isocyanate intermediate before the final product is obtained. The use of anhydrous conditions and a suitable catalyst enhances selectivity and yield.

About

CAS No 59025-55-7
English Name 2,4-Difluoro-1-isocyanatobenzene
Molecular Formula C7H3F2NO
Molecular Weight 155.1 g/mol
SMILES C1=CC(=C(C=C1F)F)N=C=O
InChIKey HNENEALJPWJWJY-UHFFFAOYSA-N
Last Updated: 2025-10-10 19:08

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