Compound Q&A

How is 2-[(2Z)-2-{[(E)-(2-Hydroxy-5-sulfophenyl)diazenyl](phenyl)methylene}hydrazino]benzoic acid (CAS: 135-52-4) typically synthesized?

Answer

2-[(2Z)-2-{[(E)-(2-Hydroxy-5-sulfophenyl)diazenyl](phenyl)methylene}hydrazino]benzoic acid
2-[(2Z)-2-{[(E)-(2-Hydroxy-5-sulfophenyl)diazenyl](phenyl)methylene}hydrazino]benzoic acid is synthesized through a multistep process involving diazotization, coupling, and esterification reactions. Commonly used catalysts include sulfuric acid for diazotization and sodium hydroxide for esterification. The overall yield is moderate, and the reaction is carried out under controlled conditions to ensure selectivity.

About

CAS No 135-52-4
English Name 2-[(2Z)-2-{[(E)-(2-Hydroxy-5-sulfophenyl)diazenyl](phenyl)methylene}hydrazino]benzoic acid
Molecular Formula C20H16N4O6S
Molecular Weight 440.44 g/mol
SMILES C1=CC=C(C=C1)C(=NNC2=C(C=CC(=C2)S(=O)(=O)O)O)N=NC3=CC=CC=C3C(=O)O
InChIKey VSSGEDASAZNGHS-IEDQNEBGSA-N
Last Updated: 2025-10-10 19:08

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