How is Methyl 2-amino-5-iodobenzoate (CAS: 77317-55-6) typically synthesized?

Methyl 2-amino-5-iodobenzoate is typically synthesized via the reaction of methyl 2-bromobenzoate with potassium iodide in the presence of a base such as potassium carbonate. The reaction yields a high purity product with good selectivity. Common solvents include dimethylformamide (DMF) or N,N-dimethylacetamide (DMA). The process usually involves refluxing the mixture until the reaction is complete, followed by purification steps such as recrystallization.