How is hexaethylene glycol monomethyl ether (CAS: 23601-40-3) typically synthesized?

Hexaethylene glycol monomethyl ether (CAS: 23601-40-3) is typically synthesized through the reaction of hexaethylene glycol with methyl iodide in the presence of a strong base such as potassium carbonate. The reaction involves the substitution of hydroxyl groups with methyl groups, resulting in high selectivity and yield. This process is carried out in an aprotic solvent to avoid side reactions.