Compound Q&A
How is (2S,3R)-2-[(Dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate hydrochloride (CAS: 2611-61-2) typically synthesized?
Answer
![(2S,3R)-2-[(Dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate hydrochloride (1:1)](https://static.chemtradehub.com/structs/261/2611-61-2-9156.webp "(2S,3R)-2-[(Dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate hydrochloride (1:1)")
It is synthesized from 2-amino-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propionic acid and dichloroacetyl chloride, using a multi-step process involving esterification and amidation reactions. The reaction is typically catalyzed by a suitable base, and the product is isolated and purified by recrystallization or column chromatography.
About
CAS No
2611-61-2
English Name
(2S,3R)-2-[(Dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate hydrochloride (1:1)
Molecular Formula
C14H19Cl3N2O6S
Molecular Weight
449.74000000000007 g/mol
SMILES
CS(=O)(=O)C1=CC=C(C=C1)C(C(COC(=O)CN)NC(=O)C(Cl)Cl)O.Cl
InChIKey
DKXJDBJNAXSJDH-XOZOLZJESA-N
Last Updated: 2025-10-10 19:08
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