Compound Q&A
What are the physical and chemical properties of Glucagon-like peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-31-glycine-32-de-L-lysine (CAS: 106612-94-6)?
Answer
Glucagon-like peptide 1 (GLP-1) is a cyclic decapeptide with a molecular weight of approximately 1320 Da. It crystallizes in a β-sheet structure. GLP-1 has poor water solubility and is highly reactive, particularly under basic conditions. It can undergo hydrolysis and racemization. For handling, it is typically formulated in a buffer solution to improve solubility and stability.
About
CAS No
106612-94-6
English Name
Glucagon-like peptide 1 (Rana catesbeiana), 3-L-glutamicacid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-31-glycine-32-de-L-lysine-
Molecular Formula
C151H228N40O47
Molecular Weight
3355.67 g/mol
SMILES
C(C1=CNC2=CC=CC=C12)[C@H](NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC1NC=NC=1)CC1C=CC=CC=1)CC1C=CC(=CC=1)O)CC1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)O)CCCNC(N)=N
InChIKey
GCYXWQUSHADNBF-AAEALURTSA-N
Last Updated: 2025-10-10 13:51
