Compound Q&A

How is 3-fluoro-4-iodobenzoic acid (CAS: 825-98-9) typically synthesized?

Answer

3-fluoro-4-iodobenzoic acid
3-Fluoro-4-iodobenzoic acid (CAS: 825-98-9) is synthesized through the iodination of 3-fluorobenzoic acid. Common methods include using sodium iodide in the presence of a base like potassium carbonate under reflux. Selectivity and yield can be improved with the use of phase transfer catalysts.

About

CAS No 825-98-9
English Name 3-fluoro-4-iodobenzoic acid
Molecular Formula C7H4FIO2
Molecular Weight 266.00899999999996 g/mol
SMILES OC(=O)c1ccc(I)c(F)c1
InChIKey KPMBAMKKTJSICO-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51

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