Compound Q&A
How is Bis(4-methylphenyl)phosphine oxide (CAS: 2409-61-2) typically synthesized?
Answer
Bis(4-methylphenyl)phosphine oxide (CAS: 2409-61-2) is typically synthesized by the condensation of 4-methylphenylphosphonic acid with diisopropylethylamine. The reaction is carried out under mild conditions, and the yield is usually over 90%. This compound can also be obtained by the reaction of 4-methylphenylphosphine with phosgene, followed by treatment with a base.
About
CAS No
2409-61-2
English Name
Bis(4-methylphenyl)phosphine oxide
Molecular Formula
C14H15OP
Molecular Weight
230.25 g/mol
SMILES
CC1=CC=C(P(C2=CC=C(C)C=C2)=O)C=C1
InChIKey
GCUWBTGMXUIKOB-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21
