Compound Q&A
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyltyrosine (CAS: 77128-72-4) typically synthesized?
Answer
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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyltyrosine is synthesized via multi-step reactions including acylation, methylation, and coupling with fluorenylmethanol. Common reagents include carbodiimides and hydroxybenzotriazoles as coupling agents, with yields varying between 70-90%. The synthesis is typically performed in polar aprotic solvents under anhydrous conditions.
About
CAS No
77128-72-4
English Name
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-methyltyrosine
Molecular Formula
C25H23NO5
Molecular Weight
417.46 g/mol
SMILES
COC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
InChIKey
JYQODLWFOPCSCS-QHCPKHFHSA-N
Last Updated: 2025-10-10 12:21
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