Compound Q&A

How is 4-Amino-2-fluorobenzoic acid (CAS: 446-31-1) typically synthesized?

Answer

4-Amino-2-fluorobenzoic acid
4-Amino-2-fluorobenzoic acid (CAS: 446-31-1) can be synthesized via a multi-step process involving the fluorination of benzoic acid followed by aminoation. Common methods include the use of fluorine gas in the presence of a Lewis acid catalyst, followed by reaction with an amine in the presence of a suitable base. The yield and selectivity can be enhanced by optimizing reaction conditions.

About

CAS No 446-31-1
English Name 4-Amino-2-fluorobenzoic acid
Molecular Formula C7H6FNO2
Molecular Weight 155.13 g/mol
SMILES C1=CC(=C(C=C1N)F)C(=O)O
InChIKey QHERSCUZBKDVOC-UHFFFAOYSA-N
Last Updated: 2025-10-08 00:58

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