Compound Q&A
How is Disodium 2'-deoxy-5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]cytidine (CAS: 102783-51-7) typically synthesized?
Answer
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Disodium 2'-deoxy-5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]cytidine is synthesized through a multistep process involving the use of phosphorus reagents, such as phosphorus oxytrichloride, and a series of condensation reactions. The yield is around 70-80% with good selectivity. Common catalysts include triethylamine and lithium chloride.
About
CAS No
102783-51-7
English Name
Disodium 2'-deoxy-5'-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]cytidine
Molecular Formula
C9H14N3Na2O13P3
Molecular Weight
511.12 g/mol
SMILES
C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O.[Na+].[Na+]
InChIKey
ABWVCNMFYVEBIB-CDNBRZBRSA-L
Last Updated: 2025-10-08 00:58
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