Compound Q&A
How is 1-Methyl-1H-pyrazole-5-carboxylic acid (CAS: 16034-46-1) typically synthesized?
Answer
1-Methyl-1H-pyrazole-5-carboxylic acid can be synthesized via amidation of 1-methylpyrazole with an appropriate carboxylic acid chloride or anhydride. Commonly, triethylamine is used as a base, and the reaction is typically performed in anhydrous organic solvents. The yield is usually around 70-80%, and the purity can be enhanced through recrystallization.
About
CAS No
16034-46-1
English Name
1-Methyl-1H-pyrazole-5-carboxylic acid
Molecular Formula
C5H6N2O2
Molecular Weight
126.11 g/mol
SMILES
CN1C(=CC=N1)C(=O)O
InChIKey
JREJQAWGQCMSIY-UHFFFAOYSA-N
Last Updated: 2025-10-08 00:58
