Compound Q&A
How is 5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine (CAS: 876343-82-7) typically synthesized?
Answer
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5-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine is commonly synthesized through electrophilic aromatic substitution reactions. A typical method involves the bromination and chlorination of 1H-pyrrolo[2,3-b]pyridine with bromine and chlorine, respectively, in the presence of a catalyst such as iron(III) chloride. The yield and selectivity are controlled by the reaction conditions and the choice of solvents.
About
CAS No
876343-82-7
English Name
5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine
Molecular Formula
C7H4BrClN2
Molecular Weight
231.48 g/mol
SMILES
c1c[nH]c2c1c(c(cn2)Br)Cl
InChIKey
FMDQNRHKEYTVBW-UHFFFAOYSA-N
Last Updated: 2025-10-07 19:42
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