Compound Q&A

How is 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 660867-80-1) typically synthesized?

Answer

2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is typically synthesized via the reaction of 2-methylpyridine with 1,3,2-dioxaborine in the presence of a base such as potassium carbonate and a palladium catalyst, such as Pd(PPh3)4. The method provides good yield and selectivity, making it a common approach for the synthesis of this compound in academic and industrial settings.

About

English Name 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Molecular Formula C12H18BNO2
Molecular Weight 219.09 g/mol
SMILES B1(OC(C(O1)(C)C)(C)C)C2=CC(=NC=C2)C
InChIKey MBTULFIFECUURA-UHFFFAOYSA-N
Last Updated: 2025-10-07 19:42

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