How is (2R)-2-[(5R,10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid (CAS: 465-18-9) typically synthesized?

The synthesis of this compound often involves a multistep process, including the preparation of the key cyclopenta[a]phenanthrene derivative, followed by hydroxylation, methylation, and esterification reactions. Common catalysts include transition metals such as palladium, and the process typically achieves a yield of around 60-70%.