Compound Q&A
How is Isopropyl trifluoroacetate (CAS: 400-38-4) typically synthesized?
Answer
Isopropyl trifluoroacetate (CAS: 400-38-4) is usually synthesized via a nucleophilic substitution reaction between trifluoroacetyl chloride and isopropanol. Commonly, triethylamine is used as a base, and the reaction is carried out under anhydrous conditions to achieve a yield of about 75-85%. The reaction is known for its high selectivity and can be performed under mild conditions without the need for additional catalysts.
About
CAS No
400-38-4
English Name
Isopropyl trifluoroacetate
Molecular Formula
C5H7F3O2
Molecular Weight
156.1 g/mol
SMILES
CC(C)OC(=O)C(F)(F)F
InChIKey
ASAXRKSDVDALDT-UHFFFAOYSA-N
Last Updated: 2025-10-07 19:42
