What regulatory guidelines apply to 4-Hydroxydihydro-2(3H)-furanone (CAS: 5469-16-9)?

4-Hydroxydihydro-2(3H)-furanone (CAS: 5469-16-9) is classified as a hazardous chemical under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) and is subject to REACH regulations in the European Union. In the United States, it falls under the jurisdiction of the FDA for food-related applications and the EPA for environmental protection. Compliance with these guidelines is essential for safety and legal operation.