Compound Q&A

How is 1,3-Dichloro-5-iodobenzene (CAS: 3032-81-3) typically synthesized?

Answer

1,3-Dichloro-5-iodobenzene
1,3-Dichloro-5-iodobenzene (CAS: 3032-81-3) is usually synthesized via the Friedel-Crafts reaction, where benzene is chlorinated first, followed by iodination. The reaction typically requires a Lewis acid catalyst like aluminum chloride and is conducted in an organic solvent. The yield is moderate, with high selectivity for the desired product.

About

CAS No 3032-81-3
English Name 1,3-Dichloro-5-iodobenzene
Molecular Formula C6H3Cl2I
Molecular Weight 272.9 g/mol
SMILES C1=C(C=C(C=C1Cl)I)Cl
InChIKey AATPRMRVLQZEHB-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54

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