Compound Q&A
How is 2-Bromo-1-chloro-4-(trifluoromethyl)benzene (CAS: 454-78-4) typically synthesized?
Answer
2-Bromo-1-chloro-4-(trifluoromethyl)benzene can be synthesized via a multistep process involving the bromination of a chlorobenzene followed by the introduction of a trifluoromethyl group. Common reagents include N-bromosuccinimide (NBS) for bromination and trifluoromethyl Grignard reagents for trifluoromethylation. The yield is typically around 70-80%, and the process involves careful temperature control and use of appropriate solvents.
About
CAS No
454-78-4
English Name
2-Bromo-1-chloro-4-(trifluoromethyl)benzene
Molecular Formula
C7H3BrClF3
Molecular Weight
259.45 g/mol
SMILES
C1=CC(=C(C=C1C(F)(F)F)Br)Cl
InChIKey
APSISOSWYXCEQX-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54
