Compound Q&A

How is 1-Amino-4-hydroxy-2-phenoxy-9,10-anthraquinone (CAS: 17418-58-5) typically synthesized?

Answer

1-Amino-4-hydroxy-2-phenoxy-9,10-anthraquinone
1-Amino-4-hydroxy-2-phenoxy-9,10-anthraquinone is usually synthesized via the oxidation of phenoxyanthraquinone followed by nucleophilic substitution at the amino position. Common methods include use of nitric acid and sodium nitrite for the oxidation step, and sodium hydroxide for the subsequent reaction. The yield is generally around 70-80%, with good selectivity towards the desired product.

About

CAS No 17418-58-5
English Name 1-Amino-4-hydroxy-2-phenoxy-9,10-anthraquinone
Molecular Formula C20H13NO4
Molecular Weight 331.33 g/mol
SMILES O=C1C2=C(C=CC=C2)C(C3=C(O)C=C(OC4=CC=CC=C4)C(N)=C13)=O
InChIKey MHXFWEJMQVIWDH-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54

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