Compound Q&A

How is 4-Fluoro-3-(trifluoromethyl)benzaldehyde (CAS: 67515-60-0) typically synthesized?

Answer

4-Fluoro-3-(trifluoromethyl)benzaldehyde
4-Fluoro-3-(trifluoromethyl)benzaldehyde (CAS: 67515-60-0) can be synthesized via the reaction of 3-(trifluoromethyl)benzaldehyde with fluoride sources such as tetrabutylammonium fluoride (TBAF). The reaction is carried out under anhydrous conditions to enhance yield and selectivity. The use of catalysts like palladium complexes can improve the reaction efficiency and minimize side products.

About

CAS No 67515-60-0
English Name 4-Fluoro-3-(trifluoromethyl)benzaldehyde
Molecular Formula C8H4F4O
Molecular Weight 192.11099999999993 g/mol
SMILES C1=CC(=C(C=C1C=O)C(F)(F)F)F
InChIKey BIUDHHGROGJSHN-UHFFFAOYSA-N
Last Updated: 2025-10-05 08:54

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