Compound Q&A

How is methyl bromo(2-chlorophenyl)acetate (CAS: 85259-19-4) typically synthesized?

Answer

Methyl bromo(2-chlorophenyl)acetate
Methyl bromo(2-chlorophenyl)acetate is synthesized through the bromination of methyl (2-chlorophenyl)acetate with an excess of bromine in the presence of a phase transfer catalyst. The reaction is carried out under anhydrous conditions to avoid side reactions. The yield is typically 80-85%, and the product is isolated by recrystallization.

About

CAS No 85259-19-4
English Name Methyl bromo(2-chlorophenyl)acetate
Molecular Formula C9H8BrClO2
Molecular Weight 263.52 g/mol
SMILES COC(=O)C(Br)c1ccccc1Cl
InChIKey HMBUCZUZRQQJQD-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42

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