Compound Q&A

How is N-(4-methylphenyl)acetamide (CAS: 103-89-9) typically synthesized?

Answer

N-(4-methylphenyl)acetamide
N-(4-methylphenyl)acetamide is typically synthesized by the reaction of p-methylbenzoyl chloride with ammonia. The reaction is usually carried out in the presence of a base like triethylamine to facilitate the formation of the amide bond. High selectivity and yield are achieved under these conditions. The process is relatively straightforward and can be scaled up for industrial production.

About

CAS No 103-89-9
English Name N-(4-methylphenyl)acetamide
Molecular Formula C9H11NO
Molecular Weight 149.19299999999998 g/mol
SMILES CC1=CC=C(C=C1)NC(=O)C
InChIKey YICAMJWHIUMFDI-UHFFFAOYSA-N
Last Updated: 2025-10-01 21:42

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