Compound Q&A

How is (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrate (CAS: 17086-28-1) typically synthesized?

Answer

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrate (1:1)
This compound is synthesized through a multi-step process involving condensation reactions, ring closures, and hydrolysis. Commonly, it is synthesized using tetracene as the starting material, with dimethylamine and various organometallic reagents. The exact synthesis route can vary, but it typically involves protecting groups and careful control of reaction conditions to achieve the desired selectivity and yield.

About

CAS No 17086-28-1
English Name (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrate (1:1)
Molecular Formula C22H26N2O9
Molecular Weight 462.46 g/mol
SMILES CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O
InChIKey XQTWDDCIUJNLTR-CVHRZJFOSA-N
Last Updated: 2025-10-01 21:42

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