Compound Q&A
How is 4-[(Trifluoromethyl)sulfanyl]benzaldehyde (CAS: 4021-50-5) typically synthesized?
Answer
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4-[(Trifluoromethyl)sulfanyl]benzaldehyde is typically synthesized via the reduction of 4-[(trifluoromethyl)thio]benzoyl chloride with sodium borohydride. This method provides good selectivity and yield. Other methods include the direct sulfonation of 4-chlorobenzaldehyde with trifluoromethyl sulfide followed by hydrogenation.
About
CAS No
4021-50-5
English Name
4-[(Trifluoromethyl)sulfanyl]benzaldehyde
Molecular Formula
C8H5F3OS
Molecular Weight
206.19 g/mol
SMILES
C1=CC(=CC=C1C=O)SC(F)(F)F
InChIKey
OPAXHVNZGUGCKW-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
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