Compound Q&A
How is 1,2-Dipalmitoyl-SN-glycero-3-phospho-L-serine (monosodium salt) (CAS: 145849-32-7) typically synthesized?
Answer
This compound can be synthesized through the condensation of palmitoyl-CoA with 1,2-diacyl-sn-glycerol and L-serine. The synthesis typically involves a nucleophilic substitution reaction followed by a condensation step. Commonly, palladium catalysts are used to improve the yield and selectivity of the reaction. The product is then converted to the monosodium salt form for better solubility and stability.
About
CAS No
145849-32-7
English Name
1,2-Dipalmitoyl-SN-glycero-3-phospho-L-serine (monosodium salt)
Molecular Formula
C38H73NNaO10P
Molecular Weight
757.9505 g/mol
SMILES
CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(C(=O)[O-])[NH3+])OC(=O)CCCCCCCCCCCCCCC.[Na+]
InChIKey
GTLXLANTBWYXGW-CEGNZRHUSA-M
Last Updated: 2025-10-01 13:51
