Compound Q&A
How is Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl- (CAS: 402-71-1) typically synthesized?
Answer
![Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-](https://static.chemtradehub.com/structs/402/402-71-1-0b7d.webp "Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-")
Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl- is typically synthesized by the reaction of 4-chloro-3-methylbenzenesulfonamide with (R)-3-chloro-2-oxo-1-(phenylmethyl)propylamine. This process involves the use of a base such as triethylamine and is carried out at room temperature. The yield can be improved by optimizing reaction conditions and using high-purity starting materials.
About
CAS No
402-71-1
English Name
Benzenesulfonamide,N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-
Molecular Formula
C17H18ClNO3S
Molecular Weight
351.8 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)CCl
InChIKey
MQUQNUAYKLCRME-INIZCTEOSA-N
Last Updated: 2025-10-01 13:51
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