Compound Q&A

How is N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE (CAS: 53678-77-6) typically synthesized?

Answer

N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
N-AcetylMuramyl-L-Alanyl-D-Isoglutamine (CAS: 53678-77-6) is typically synthesized through a multi-step process involving peptide coupling reactions. Key steps include the formation of the peptide bond between N-acetyl muramine and L-alanine, followed by the coupling with D-isoglutamine. The synthesis often employs coupling reagents like 1-hydroxybenzotriazole (HOBt) and N,N′-carbonyldiimidazole (CDI) with appropriate catalysis to enhance selectivity and yield.

About

CAS No 53678-77-6
English Name N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
Molecular Formula C19H32N4O11
Molecular Weight 492.48 g/mol
SMILES CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
InChIKey BSOQXXWZTUDTEL-QAQREVAFSA-N
Last Updated: 2025-10-01 13:51

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