Compound Q&A
How is Methyl 2-chloronicotinate (CAS: 40134-18-7) typically synthesized?
Answer
Methyl 2-chloronicotinate is typically synthesized by chlorinating nicotinic acid with methylamine. The reaction is carried out in the presence of a catalyst such as aluminum chloride, resulting in a high yield. The reaction is selective, and the product is isolated by recrystallization. This process is efficient and can be scaled up for industrial production.
About
CAS No
40134-18-7
English Name
Methyl 2-chloronicotinate
Molecular Formula
C7H6ClNO2
Molecular Weight
171.58 g/mol
SMILES
COC(=O)C1=C(N=CC=C1)Cl
InChIKey
MYGAJZBZLONIBZ-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
