Compound Q&A

How is Ethyl 1H-pyrazol-3-ylacetate (CAS: 82668-50-6) typically synthesized?

Answer

Ethyl 1H-pyrazol-3-ylacetate
Ethyl 1H-pyrazol-3-ylacetate can be synthesized via the condensation of 1H-pyrazol-3-yl acetic acid and ethylamine. This reaction typically occurs under mild conditions, utilizing an appropriate solvent such as tetrahydrofuran (THF) or acetonitrile. The yield can be increased by using a catalytic amount of a Lewis acid like aluminum chloride to improve the reaction selectivity and conversion rate.

About

CAS No 82668-50-6
English Name Ethyl 1H-pyrazol-3-ylacetate
Molecular Formula C7H10N2O2
Molecular Weight 154.17 g/mol
SMILES CCOC(=O)CC1=CC=NN1
InChIKey MZLKPCAZQWMXFD-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51

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