Compound Q&A

How is methyl (E)-2-((3S,6'R,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate (CAS: 6859-01-4) typically synthesized?

Answer

methyl (E)-2-((3S,6'R,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate
This compound is typically synthesized by a multi-step process involving the preparation of the indolizinone ring followed by introduction of the methoxy group and the acrylate functional group. Common catalysts include Lewis acids, and the reaction conditions are optimized for high yield and selectivity. The exact synthesis route may vary depending on the specific starting materials and the desired product purity.

About

CAS No 6859-01-4
English Name methyl (E)-2-((3S,6'R,7'S,8a'S)-6'-ethyl-2-oxo-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)-3-methoxyacrylate
Molecular Formula C22H28N2O4
Molecular Weight 384.48 g/mol
SMILES CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O
InChIKey DAXYUDFNWXHGBE-VKCGGMIFSA-N
Last Updated: 2025-10-01 13:51

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