Compound Q&A

How is 2-amino-N-cyclohexyl-N-methylbenzene-1-sulfonamide (CAS: 70693-59-3) typically synthesized?

Answer

2-amino-N-cyclohexyl-N-methylbenzene-1-sulfonamide
2-Amino-N-cyclohexyl-N-methylbenzene-1-sulfonamide (CAS: 70693-59-3) can be synthesized by the condensation of N-methyl-N-cyclohexyl-2-benzamidoacetamide with 1-hydroxy-2-naphthoic acid in the presence of a base such as sodium hydroxide. The reaction involves the formation of an amide bond and a sulfonamide linkage. The yield is typically around 85%, and the selectivity is high due to the specific reactivity of the amino and sulfonamido groups.

About

CAS No 70693-59-3
English Name 2-amino-N-cyclohexyl-N-methylbenzene-1-sulfonamide
Molecular Formula C13H20N2O2S
Molecular Weight 268.38 g/mol
SMILES CN(C1CCCCC1)S(=O)(=O)C2=CC=CC=C2N
InChIKey IPEHSCPRVOWQFQ-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51

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