Compound Q&A
How is 1-Nitro-3,5-bis(trifluoromethyl)benzene (CAS: 328-75-6) typically synthesized?
Answer
1-Nitro-3,5-bis(trifluoromethyl)benzene is typically synthesized via nitration of 3,5-bis(trifluoromethyl)benzene with concentrated nitric acid in the presence of sulfuric acid as a catalyst. The reaction is usually performed under controlled conditions to achieve good yield and selectivity. The product can then be purified using standard techniques such as recrystallization.
About
CAS No
328-75-6
English Name
1-Nitro-3,5-bis(trifluoromethyl)benzene
Molecular Formula
C8H3F6NO2
Molecular Weight
259.1 g/mol
SMILES
C1=C(C=C(C=C1C(F)(F)F)[N+](=O)[O-])C(F)(F)F
InChIKey
GMUWJDVVXLBMEZ-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51
